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I don't know how to create a crossword puzzle, so that my patient can do this exercice while, from time to time, an image appear really quickly. Can you please help me?
What kind of puzzle do you have in mind? Basically what you can do is create a custom form that consists of labels and text inputs, but setting this up will be a pain. You could draw a grid on a canvas with small text in some fields, but that isn't much more efficient. One option would also be to use a screenshot of a puzzle and present that on the screen, but this has the disadvantage that responding will be tricky.
To some extent it also depends on the size of the puzzle that you have in mind. Can you maybe give more details?